DCR Lectures

DCR Lecture - Wednesday, 27 March 2024

12.45 – 1.30 PM via Zoom.

Reflections on Event Adjudication in Cardiovascular Outcome Trials

Event adjudication is widely applied in cardiovascular outcome trials (CVOTs) to standardize endpoint ascertainment and remove potential bias due to spurious events. I will present selected findings from a recent individual-participant meta-analysis that we undertook to evaluate the effect of event adjudication on heart failure outcomes. In the second part, I will highlight some statistical challenges around milestone event prediction for CVOTs.

Dr Simon Wandel holds a master's in Statistics and a PhD in Medical Statistics/Epidemiology (both from the University of Bern). Since 2021, he has been the Global Group Head of Biostatistics for atherosclerotic cardiovascular disease at Novartis Pharma AG.

Please register here in advance.
After registration, you will receive more information via email.

This lecture is cancelled.

We apologize for the inconvenience.

DCR Lecture - Wednesday, 28 February 2024

12.45 – 1.30 PM via zoom.

Phase 1 Trials in the Era of Active Drugs

The therapeutic landscape in cancer has rapidly evolved with dramatic and prolonged responses observed in certain tumor types. This also led to a rethinking of early-phase clinical trial designs. In this talk, Prof. Dr. Hans Prenen would like to discuss the evolution of the process of optimally developing a novel cancer agent.

Lecturer: Prof. Dr. Hans Prenen obtained his medical degree and PhD at the Catholic University Leuven (Belgium). He is currently the head of the Medical Oncology Department at the University Hospital Antwerp and director of the Oncology Clinical Trial Unit. He is a member of several scientific organizations including the Belgian Society of Medical Oncology (board member since 2015) and the European Society of Medical Oncology (scientific committee). He is a recognized international expert in the field of cancer and is regularly invited to national and international meetings and has published more than 180 peer-reviewed scientific papers. He is the principal investigator of multiple clinical trials focusing on phase 1 and basket trials.  His research interests relate to translational studies on targeted therapies, new anticancer therapies, and understanding the molecular changes induced by anticancer therapy.

Wednesday 28 February 2024 | 12.45 - 1.30 pm via Zoom

Please register here.

DCR Lecture Wednesday, 31 January 2024
12.45 – 1.30 PM via zoom.
 

Health Economics and Evidence Generation to Support Medical Decision-Making

Lecturer: Dr.Gian Luca Di Tanna, Professor of BioStatistics and Health Economics, Head of Research, Department of Business Economics, Health & Social Care (DEASS), SUPSI • Professorial Fellow of The George Institute for Global Health and UNSW

Prof. Dr. Gian Luca Di Tanna has a PhD in Health Economics, an MPhil/PhD in Medical Statistics, and an MSc in Data Intelligence and Decision Analyses. He is an Accredited Statistician (AStat) of the Statistical Society of Australia and a Chartered Statistician (CStat) of the Royal Statistical Society (UK).
He is the Chair-elect of the Statistical Methods in Health Economics and Outcomes Research Special Interest Group of the ISPOR - The Professional Society for Health Economics and Outcomes Research, Statistical Editor of two Cochrane groups, the Breast Cancer and the Consumer and Communication Review Group.

Please register here in advance.
After registration, you will receive more information via email.